Clinical Trial Manager – Real World Evidence

About the role

ICON plc is seeking a Clinical Trial Manager (CTM) to lead operational oversight of Real World Evidence (RWE) clinical studies across multiple locations. The CTM will coordinate site management, monitoring activities, and ensure delivery of high‑quality data within scope, timeline and budget.

Key responsibilities

• Plan and manage all clinical operations aspects of RWE trials, ensuring adherence to timelines, budget, and quality standards.
• Oversee Site Management Associates (SMAs) and Clinical Research Associates (CRAs) in site activation, remote and onsite monitoring, document collection, regulatory approvals and site close‑out.
• Develop site monitoring and management plans, conduct training for the clinical team, and review trip reports.
• Identify risks, define mitigation strategies, and monitor metrics and dashboards.
• Collaborate with RWS Project Manager, Finance, and Data Management to meet project objectives.
• Provide sponsors with metrics, study updates, and act as the primary client‑facing contact.

Required profile

• University degree in medicine, science or equivalent.
• At least 2 years of experience in clinical trial management within a CRO or pharmaceutical company.
• Solid experience managing RWE clinical trials, preferably Phase III or IV across therapeutic areas.
• Proven ability to drive clinical deliverables and manage competing priorities.

Required skills

• Experience with Clinical Trial Management Systems (CTMS).
• Risk‑based monitoring expertise.